He married Sarah Johnson. Sarah was born on September 20, 1765. She was the daughter of Philip and Sarah Johnson.
Nathaniel and Sarah's children included:
Elizabeth Yerkes (1787),
Philip Yerkes (1789),
Nancy Yerkes (1793),
Mary Yerkes (1796),
William Yerkes (1798),
Josiah Yerkes (1800, married Margaret Knight), and
Sarah Yerkes Frost (1802, married John C. Frost).
Nathaniel was the executor of his father's will and received 100 acres in Moreland.
The family appeared in the 1790 census in the Manor of Moreland. The family consisted of one male sixteen or older (Nathaniel), one male younger than sixteen (Philip) and two females (Sarah, Elizabeth).
On August 19, 1799 he conveyed certain water rights on Pennypack Creek to George Shelmire.
On April 1, 1818 they conveyed their land to Joel K. Mann and moved to Romulus, Senaca County, New York. Nathaniel died on June 5, 1831 in Romulus and Sarah died on April 20, 1835.
The Manor of Moreland was composed of a tract of ten thousand acres, and was created, in 1682, by a grant from William Penn to Dr. Nicholas More. Most of the Manor was in Philadelphia County, but is now
Moreland Township, Montgomery County, Pennsylvania.
Byberry is a township in the northeast corner of Philadelphia County, Pennsylvania. The Walton brothers were early settlers. Moreland Township was just west of Byberry. When Montgomery County broke off in 1784, Moreland was divided into two townships, both called Moreland. In 1917 the Montgomery County Moreland split into Upper Moreland Township and Lower Moreland Township.